BioXGEM.
KIDFamMap
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Example1
Example2
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
2 ABL2 related diseases
hsa05416
Viral myocarditis
OMIM
(164690)
Leukemia, acute myeloid, with eosinophilia
Summary of query kinase
Query kinase
ABL2 (
P42684
)
Kinase group
TK
Number of conformation types
3
Number of structural templates
3 (
Total 103 inhibitors
)
Number of ABL2 related diseases
2 (
hsa05416
OMIM:164690
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
1
2XYNA_VX6
(ABL2)
TK
VX-680
I
79
101
105
A
2XYNA_VX6
(ABL2)
TK
VX-680
I
79
101
105
79
101
105
B
1
3HMIA_DKI
(ABL2)
TK
5-AMINO-3-{[...
I
2
2
2
B
3HMIA_DKI
(ABL2)
TK
5-AMINO-3-{[...
I
2
2
2
2
2
2
E
1
3GVUA_STI
(ABL2)
TK
Imatinib
II
12
177
42
E
3GVUA_STI
(ABL2)
TK
Imatinib
II
12
177
42
12
177
42