BioXGEM.
KIDFamMap
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Example2
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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
2 PRKCQ related diseases
H00408
Type I diabetes mellitus
hsa05162
Measles
Summary of query kinase
Query kinase
PKN2 (
Q16513
),
reference kinase: PRKCQ
(
Q04759
)
Kinase group
AGC
Number of conformation types
1
Number of structural templates
2 (
Total 404 inhibitors
)
Number of PRKCQ related diseases
2 (
H00408
hsa05162
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
2
1XJDA_STU
(PRKCQ)
AGC
staurosporine
I
121
101
106
A
1XJDA_STU
(PRKCQ)
AGC
staurosporine
I
121
101
106
121
101
106
A
2JEDA_LG8
(PRKCQ)
AGC
5-Arylidene-...
I
67
19
87
67
19
87