Protein Surface  Ribbon
Inhibitor 3D3
  ATP Location
Motifs All P-loop B3 Hinge
C-loop A-loop
Select Anchor
Summary of 2 kinases in KIF 2CGXA_3D3 (CHEK1, PDB code: 2CGX, chain A)

Multiple sequence alignment of family kinases

Conserved residues:   
                            
Group      Kinase           
CAMK       CHEK1        203 
TKL        LIMK1        339 



-WDLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCP--ENI-KKEICINKMLNHENVVKFYGHRREGNIQYLFLEYCSGGELFDRIEPDI--GMPEPDAQRFFHQLMAGVVYLHGIGITHRDIKPENLLLDERDNLKISDFGLATVFR-YNNRERLL------------NK---MCGTLPYVAPELLKRREFHAEPVDVWSCGIVLTAMLA-GELPWDQP---SDSCQEYSDWKEKKTYLNPWKKIDSAPLALLHKILVENPSARITIPDIKKDRW-Y
LI-HGEVLGKGCFGQAIKVTHRETGEVMVMKELI--RFD-EETQRTFL-KEVKVMRCLEHPNVLKFIGVLYKDKRLNFITEYIKGGTLRGIIK-SMDSQYPWSQRVSFAKDIASGMAYLHSMNIIHRDLNSHNCLVRENKNVVVADFGLARLM-V-D--EKTQPEGLRSLKKPDRKKRYTVVGNPYWMAPEMIN-GRSYDEKVDVFSFGIVLCEIIGRVNADPDYLPRTMDFGLNVRGFLDRYCPPNCP----PSFFPITVRCCDLDPEKRPSFVKLEH---WL