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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CAMK CHEK2 203
CAMK CHEK1 9
CAMK MAPKAPK2 64
Other NEK2 8
-YI--MSKTLGSGACGEVKLAFERKTCKKVAIKIISKRKFAIGSAREADPALNVETEIEILKKL-NHPCIIKIKNFF-D----AEDYYIVLELMEGGELFDKVV----GNKRLKEATCKLYFYQMLLAVQYLHEN-----GIIHRDLKPENVLLSSQEEDCLIKITDFGHSKI---LGETSLMRTLCGTPTYLAPEVLVSVGTAGYNRAVDCWSLGVILFICLSGYPPFSEH---RTQVSLKDQITSGKYNFIPEVWAEVSEKALDLVKKLLVVDPKARFTTEEALRHPWL-
--W-DLVQTLGEGAYGEVQLAVNRVTEEAVAVKIVDMKRAVDCPENI-KK------EICINKML-NHENVVKFYGHRRE----GNIQYLFLEYCSGGELFDRIE----PDIGMPEPDAQRFFHQLMAGVVYLHGI-----GITHRDIKPENLLLDERDNL---KISDFGLATVFRYNNRERLLNKMCGTLPYVAPELLK--RREFHAEPVDVWSCGIVLTAMLAGELPWDQP---SDSCQEYSDWKEKKTYLNPWKKI--DSAPLALLHKILVENPSARITIPDIKKDRW-Y
KVT---SQVLGLGINGKVLQIFNKRTQEKFALKMLQDCPKAR-------R------EVELHWRASQCPHIVRIVDVYENLYAGRKCLLIVMECLDGGELFSRIQD--RGDQAFTEREASEIMKSIGEAIQYLHSI-----NIAHRDVKPENLLYTSKRPNAILKLTDFGFAKE---TTSHNSLTTPCYTPYYVAPEVLG---PEKYDKSCDMWSLGVIMYILLCGYPPFYSNHGLAISPGMKTRIRMGQYEFPNPEWSEVSEEVKMLIRNLLKTEPTQRMTITEFMNHPWI-
---YEVLYTIGTGSYGRCQKIRRKSDGKILVWKELDYGSMTEAEKQMLVS------EVNLLREL-KHPNIVRYYDRIIDR--TNTTLYIVMEYCEGGDLASVITKGTKERQYLDEEFVLRVMTQLTLALKECHRRSDGGHTVLHRDLKPANVFLDGKQNV---KLGDFGLARIL--NHDTSFAKTFVGTPYYMSPEQMN---RMSYNEKSDIWSLGCLLYELCALMPPFTAF----SQKELAGKIREGKFRRIPYRY---SDELNEIITRMLNLKDYHRPSVEEILENPL-I
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