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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
TK ERBB2 203
TK EGFR 712
TK TNK2 150
LRKVKVLGSGAFGTVYKGIWIPDGENVKIPVAIKVLRE--NTSPKANKEILDEAYVMAGVGSPYVSRLLGICLTSTVQLVTQLMPYGCLLDHVRENRGRLGSQDLLNWCMQIAKGMSYLEDVRLVHRDLAARNVLVKSPNHVKITDFGLARLL-DIDETEYHADGGKVPIKWMALESILRRRFTHQSDVWSYGVTVWELMTFGAKPYDGIPAREIPDLL-EKGERLPQPPICTIDVYMIMVKCWMIDSECRPRFRELVSEF--
FKKIKVLGSGAFGTVYKGLWIPEGEKVKIPVAIKELRE--ATSPKANKEILDEAYVMASVDNPHVCRLLGICLTSTVQLITQLMPFGCLLDYVREHKDNIGSQYLLNWCVQIAKGMNYLEDRRLVHRDLAARNVLVKTPQHVKITDFGLAKLL-GAEEKEYHAEGGKVPIKWMALESILHRIYTHQSDVWSYGVTVWELMTFGSKPYDGIPASEISSIL-EKGERLPQPPICTIDVYMIMVKCWMIDADSRPKFRELI--IEF
LRLLEKLGDGSFGVVRRGEWD-APSGKTVSVAVKCLKPDVLSQPEAMDDFIREVNAMHSLDHRNLIRLYGVVLTPPMKMVTELAPLGSLLDRLRKHQGHFLLGTLSRYAVQVAEGMGYLESKRFIHRDLAARNLLLATRDLVKIGDFGLMRALPQNDDHYVMQEHRKVPFAWCAPESLKTRTFSHASDTWMFGVTLWEMFTYGQEPWIGLNGSQILHKIDKEGERLPRPEDCPQDIYNVMVQCWAHKPEDRPTFVALRDFL--
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