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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
STE PAK1 203
CMGC GSK3B 56
CAMK PIM1 38
YTRFEKIGQGASGTVYTAMDVATGQEVAIKQMNLQQQPKKELII--N----EILVMRENKNPN--IVNYLDSYLV----GDELW--VVMEYLAGG--SLTDVVT-----ETCMDEGQIAAVCRECLQALEFLHSNQVIHRDIKSDNILLG-MDGSVKLTDFGFCAQITPEQSKRSTMVGTPYWMAPEVVT-RKAYGPKVDIWSLGIMAIEMIEGEPPYLNENPLRALYLIATNGTPELQNPEKLS--------------------------AIFRDFLNRCLEMDVEKRGSAKELLQHQFL
YTDTKVIGNGSFGVVYQAKLCDSGELVAIKKVLQDKRFKNR----------ELQIMRKLDHCN--IVRLRYFFYSSGEKKDEVYLNLVLDYVPETVYRVA---RHYSRAKQTLPVIYVKLYMYQLFRSLAYIHSFGICHRDIKPQNLLLDPDTAVLKLCDFGSAKQ-LVRGEPNVSYICSRYYRAPELIFGATDYTSSIDVWSAGCVLAELLLGQPIFPGDSGVDQLVEIIKVLGTPTREQIREMNPNYTEFKFPQIKAHPWTKVFRPRTPPEAIALCSRLLEYTPTARLTPLEACAHSFF
YQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKVSSGFSGVIRLLDWFER----PDSFV--LILERPEPV-QDLFDFIT----ERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGA--LLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHD---------EEIIRGQVFFRQRVS--------------------------SECQHLIRWCLALRPSDRPTFEEIQNHPWM
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