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Multiple sequence alignment of family kinases
Conserved residues:
Group Kinase
CAMK PIM1 203
CMGC CDK2 4
AGC PRKCA 339
-YQVGPLLGSGGFGSVYSGIRVSDNLPVAIKHVEKDRISDWGELPNGTRVPMEVVLLKKV-SSGFSGVIRLLDWFERPDSFVLILERPEPVQDLFDFIT--ERGALQEELARSFFWQVLEAVRHCHNCGVLHRDIKDENILIDLNRGELKLIDFGSGA--LLKDTVYTDFDGTRVYSPPEWIRYHRYHGRSAAVWSLGILLYDMVCGDIPFEHD---------EEIIRGQVFFRQRVS--------------------------SECQHLIRWCLALRPSDRPTFEEIQNHPWM--------------
-FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIR----EISLLKEL-NHPN--IVKLLDVIHTENKLYLVFEFLHQ--DLKKFMDASALTGIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLIN-TEGAIKLADFGLARAFGVPVRTYTHEVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVTRRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF--------------
F-NFLMVLGKGSFGKVMLADRKGTEELYAIKILKKDVVIQDDDVECTM---VEKRVLALLDKPPF--LTQLHSCFQTVDRLYFVMEYVNGG-DLMYHIQ--QVGKFKEPQAVFYAAEISIGLFFLHKRGIIYRDLKLDNVMLD-SEGHIKIADFGMCKEHMMDGVTTRTFCGTPDYIAPEIIA-YQPYGKSVDWWAYGVLLYEMLAGQPPFDGE---DEDELFQSIMEHNVSYPKSLS--------------------------KEAVSVCKGLMTKHPAKRLGC---------GPEGERDVREHAFF
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