Protein Surface  Ribbon
Inhibitor 24A
  ATP Location
Motifs All P-loop B3 Hinge
C-loop A-loop
Select Anchor
Summary of 3 kinases in KIF 2BDFA_24A (SRC, PDB code: 2BDF, chain A)

Multiple sequence alignment of family kinases

Conserved residues:   
                            
Group      Kinase           
TK         SRC          203 
TK         ABL1         261 
CMGC       CDK2           4 



L-RLEVKLGQGCFGEVWMGTWN-GTTRVAIKTLK-PGTM-SPEAFL-QEAQVMKKLRHEKLVQLYAVVS-EEPIYIVTEYMSKGSLLDFLK---GETGKYLRLPQLVDMAAQIASGMAYVERMNYVHRDLRAANILVGENLVCKVADFGLARLIE--DNEYTARQGAKFPIKWTAPEAAL-YGRFTIKSDVWSFGILLTELTTKGRVPYPGMVNREVLDQVERGYRMPCPPECP----------------------------ESLHDLMCQCWRKEPEERPTFEYLQAF--L
-ITMKHKLGGGQYGEVYEGVWKKYSLTVAVKTLK-EDTM-EVEEFL-KEAAVMKEIKHPNLVQLLGVCTREPPFYIITEFMTYGNLLDYLR---ECNRQEVNAVVLLYMATQISSAMEYLEKKNFIHRDLAARNCLVGENHLVKVADFGLSRLMT--GDTYTAHAGAKFPIKWTAPESLA-YNKFSIKSDVWAFGVLLWEIATYGMSPYPGIDLSQVYELLEKDYRMERPEGCP----------------------------EKVYELMRACWQWNPSDRPSFAEIHQA--F
-FQKVEKIGEGTYGVVYKARNKLTGEVVALKKIRLDTETEGVPSTAIREISLLKELNHPNIVKLLDVIHTENKLYLVFEFLHQ-DLKKFMDASALT---GIPLPLIKSYLFQLLQGLAFCHSHRVLHRDLKPQNLLINTEGAIKLADFGLARAFGVPVRTYTH---EVVTLWYRAPEILLGCKYYSTAVDIWSLGCIFAEMVT-RRALFPGDSEIDQLFRIFRTLGTPDEVVWPGVTSMPDYKPSFPKWARQDFSKVVPPLDEDGRSLLSQMLHYDPNKRISAKAALAHPFF