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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Summary of query kinase
Query kinase
AXL (
P30530
)
Kinase group
TK
Number of conformation types
0
Number of structural templates
26 (
Total 96 inhibitors
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
14
2IVUA_ZD6
(RET)
TK
Vandetanib
I
83
291
121
A
2IVUA_ZD6
(RET)
TK
Vandetanib
I
83
291
121
83
291
121
A
3CKXA_STU
(STK24)
TK
staurosporine
I
176
104
141
176
104
141
A
1AQ1A_STU
(CDK2)
TK
staurosporine
I
195
76
118
195
76
118
A
1PKDA_UCN
(CDK2)
TK
UCN 02
I
195
67
118
195
67
118
A
1XJDA_STU
(PRKCQ)
TK
staurosporine
I
121
101
106
121
101
106
A
2VTTA_LZD
(CDK2)
TK
pyrazole dia...
I
158
42
111
158
42
111
A
2WIHA_P48
(CDK2)
TK
VX_680
I
111
425
105
111
425
105
A
1R78A_FMD
(CDK2)
TK
4-alkynyl ox...
I
127
24
97
127
24
97
A
2IW6A_QQ2
(CDK2)
TK
2iw6
I
112
209
86
112
209
86
A
2B55A_D31
(CDK2)
TK
D31
I
27
87
53
27
87
53
A
2JEDA_LG8
(PRKCQ)
TK
5-Arylidene-...
I
67
19
87
67
19
87
A
1OI9A_N20
(CDK2)
TK
NU-6086
I
52
80
61
52
80
61
A
3PJ3A_04L
(BTK)
TK
Imatinib
II
99
113
134
99
113
134
A
3PIYA_585
(BTK)
TK
R-406
I
93
17
123
93
17
123
B
12
3BKBA_STU
(FES)
TK
staurosporine
I
131
107
138
B
3BKBA_STU
(FES)
TK
staurosporine
I
131
107
138
131
107
138
B
3CBLA_STU
(FES)
TK
staurosporine
I
131
107
138
131
107
138
B
3CD3A_STU
(FES)
TK
staurosporine
I
131
107
138
131
107
138
B
3LCSA_STU
(ALK)
TK
staurosporine
I
73
100
109
73
100
109
B
1H00A_FAP
(CDK2)
TK
AC1NAE4F
I
50
94
75
50
94
75
B
3F5PA_741
(IGF1R)
TK
3-cyanoquino...
I
60
123
81
60
123
81
B
3LW0A_CCX
(IGF1R)
TK
5-vinyl-3-py...
III
53
30
101
53
30
101
B
1H07A_MFP
(CDK2)
TK
AC1NAKJQ
I
90
241
80
90
241
80
B
2XB7A_GUI
(ALK)
TK
NVP-TAE684
I
71
66
107
71
66
107
B
3EKNA_GS3
(INSR)
TK
pyrrolo[2,3-...
I
90
215
127
90
215
127
B
3AOXA_EMH
(ALK)
TK
BIRB_796
I
34
28
85
34
28
85
B
3EKKA_GS2
(INSR)
TK
pyrrolo[2,3-...
I
33
131
65
33
131
65