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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
1 ALPK3 related diseases
614181
REtinitis pigmentosa 62
Summary of query kinase
Query kinase
MAK (
Q96L96
)
Kinase group
Atypical
Number of conformation types
0
Number of structural templates
35 (
Total 10 inhibitors
)
Number of ALPK3 related diseases
1 (
614181
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
26
3EQFA_KSA
(MAP2K1)
Atypical
k-252a
I
42
51
57
A
3EQFA_KSA
(MAP2K1)
Atypical
k-252a
I
42
51
57
42
51
57
A
2JAMA_J60
(CAMK1G)
Atypical
SU11652
I
50
65
32
50
65
32
A
3CKXA_STU
(STK24)
Atypical
staurosporine
I
176
104
141
176
104
141
A
2XIKA_J60
(STK25)
Atypical
SU11652
I
59
49
65
59
49
65
A
1XJDA_STU
(PRKCQ)
Atypical
staurosporine
I
121
101
106
121
101
106
A
3FMEA_STU
(MAP2K6)
Atypical
staurosporine
I
28
15
20
28
15
20
A
2JAVA_5Z5
(NEK2)
Atypical
pyrrollylact...
I
25
40
24
25
40
24
A
1PKDA_UCN
(CDK2)
Atypical
UCN 02
I
195
67
118
195
67
118
A
2DQ7X_STU
(FYN)
Atypical
staurosporine
I
91
74
124
91
74
124
A
2VTQA_LZA
(CDK2)
Atypical
pyrazole dia...
I
36
25
31
36
25
31
A
1Q3DA_STU
(GSK3B)
Atypical
staurosporine
I
115
71
61
115
71
61
A
2HY81_1ST
(PAK1)
Atypical
UCN 02
I
58
20
75
58
20
75
A
2VTTA_LZD
(CDK2)
Atypical
pyrazole dia...
I
158
42
111
158
42
111
A
1AQ1A_STU
(CDK2)
Atypical
staurosporine
I
195
76
118
195
76
118
A
1QPDA_STU
(LCK)
Atypical
staurosporine
I
115
76
126
115
76
126
A
2HZ4A_4ST
(ABL1)
Atypical
staurosporine
I
159
103
156
159
103
156
A
3A4OX_STU
(LYN)
Atypical
staurosporine
I
73
70
88
73
70
88
A
2VU3A_LZE
(CDK2)
Atypical
AT7519
I
35
22
29
35
22
29
A
1BYGA_STU
(CSK)
Atypical
staurosporine
I
85
72
123
85
72
123
A
1QPJA_STU
(LCK)
Atypical
staurosporine
I
115
76
126
115
76
126
A
3BLRA_CPB
(CDK9)
Atypical
BIIVYFLTOXDA...
I
48
17
41
48
17
41
A
1NVQA_UCN
(CHEK1)
Atypical
UCN 02
I
179
65
79
179
65
79
A
1SM2A_STU
(ITK)
Atypical
staurosporine
I
99
104
128
99
104
128
A
2J7TA_274
(STK10)
Atypical
SU11274
I
66
20
77
66
20
77
A
1NVRA_STU
(CHEK1)
Atypical
staurosporine
I
179
71
79
179
71
79
A
1SNUA_STU
(ITK)
Atypical
staurosporine
I
99
104
128
99
104
128
B
9
3CD3A_STU
(FES)
Atypical
staurosporine
I
131
107
138
B
3CD3A_STU
(FES)
Atypical
staurosporine
I
131
107
138
131
107
138
B
1OKYA_STU
(PDPK1)
Atypical
staurosporine
I
179
67
109
179
67
109
B
1WVYA_STU
(DAPK1)
Atypical
staurosporine
I
83
23
55
83
23
55
B
3EFWA_AK8
(AURKA)
Atypical
3efw
I
100
59
105
100
59
105
B
1OKZA_UCN
(PDPK1)
Atypical
UCN 02
I
179
60
109
179
60
109
B
3MIYA_B49
(ITK)
Atypical
Sunitinib
I
70
74
110
70
74
110
B
2FVDA_LIA
(CDK2)
Atypical
[4-Amino-2-[...
I
39
16
29
39
16
29
B
3BKBA_STU
(FES)
Atypical
staurosporine
I
131
107
138
131
107
138
B
3CBLA_STU
(FES)
Atypical
staurosporine
I
131
107
138
131
107
138