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Diseases
Inhibitor-Anchor Map
Family Anchors
Kinase-Inhibitor Family
Template
Protein
Surface
Ribbon
Inhibitor
ATP Location
Pocket
ATP
NLP
HAP
CLP
SP
Summary of query kinase
Query kinase
NEK5 (
Q6P3R8
)
Kinase group
Other
Number of conformation types
0
Number of structural templates
43 (
Total 22 inhibitors
)
Select
Template
Comformation
Type
No. of
Templates
Representative
Template
Kinase
Group
Representative
Inhibitor
Inhibitor
Type
No. of
Kinases
No. of
Inhibitors
No. of
Diseases
A
30
2F4JA_VX6
(ABL1)
Other
VX-680
I
110
109
134
A
2F4JA_VX6
(ABL1)
Other
VX-680
I
110
109
134
110
109
134
A
1NXKA_STU
(MAPKAPK2)
Other
staurosporine
I
110
67
51
110
67
51
A
1YHSA_STU
(PIM1)
Other
staurosporine
I
78
64
50
78
64
50
A
2WIHA_P48
(CDK2)
Other
VX_680
I
111
425
105
111
425
105
A
2HZ4A_4ST
(ABL1)
Other
staurosporine
I
159
103
156
159
103
156
A
3HMOA_STU
(TTK)
Other
staurosporine
I
27
50
20
27
50
20
A
2XYNA_VX6
(ABL2)
Other
VX-680
I
79
101
105
79
101
105
A
3E5AA_VX6
(AURKA)
Other
VX-680
I
57
107
93
57
107
93
A
1PKDA_UCN
(CDK2)
Other
UCN 02
I
195
67
118
195
67
118
A
1QPDA_STU
(LCK)
Other
staurosporine
I
115
76
126
115
76
126
A
1AQ1A_STU
(CDK2)
Other
staurosporine
I
195
76
118
195
76
118
A
1QPJA_STU
(LCK)
Other
staurosporine
I
115
76
126
115
76
126
A
1NVQA_UCN
(CHEK1)
Other
UCN 02
I
179
65
79
179
65
79
A
1SM2A_STU
(ITK)
Other
staurosporine
I
99
104
128
99
104
128
A
1NVRA_STU
(CHEK1)
Other
staurosporine
I
179
71
79
179
71
79
A
1SNUA_STU
(ITK)
Other
staurosporine
I
99
104
128
99
104
128
A
2XNPA_WCX
(NEK2)
Other
4-{5-[(1-Met...
I
12
34
17
12
34
17
A
3IKAA_0UN
(EGFR)
Other
2jkk
I
76
120
108
76
120
108
A
3L8XA_N4D
(MAPK14)
Other
3cg2
I
91
104
65
91
104
65
A
3PIYA_585
(BTK)
Other
R-406
I
93
17
123
93
17
123
A
3PJ3A_04L
(BTK)
Other
Imatinib
II
99
113
134
99
113
134
A
3GFWA_S22
(TTK)
Other
1-(4-(4-(2-(...
I
21
4
18
21
4
18
A
1OPLA_P16
(ABL1)
Other
PD166326
I
89
70
123
89
70
123
A
2I40A_BLZ
(CDK2)
Other
2i40
I
34
95
16
34
95
16
A
2XNMA_WGZ
(NEK2)
Other
benzimidazol...
I
12
93
9
12
93
9
A
2FO0A_P16
(ABL1)
Other
PD166326
I
89
70
123
89
70
123
A
2XNNA_430
(NEK2)
Other
Kinome_3463
I
12
83
9
12
83
9
A
2G2HA_P16
(ABL1)
Other
PD166326
I
89
70
123
89
70
123
A
2XNOA_ED8
(NEK2)
Other
5-{6-[(1-Met...
I
12
82
9
12
82
9
A
2HZIA_JIN
(ABL1)
Other
PD180970
I
90
77
120
90
77
120
B
12
3D7TA_STU
(CSK)
Other
staurosporine
I
70
68
99
B
3D7TA_STU
(CSK)
Other
staurosporine
I
70
68
99
70
68
99
B
1OKYA_STU
(PDPK1)
Other
staurosporine
I
179
67
109
179
67
109
B
1OKZA_UCN
(PDPK1)
Other
UCN 02
I
179
60
109
179
60
109
B
2ITQA_STU
(EGFR)
Other
staurosporine
I
80
85
106
80
85
106
B
3LCSA_STU
(ALK)
Other
staurosporine
I
73
100
109
73
100
109
B
2ITUA_STU
(EGFR)
Other
staurosporine
I
80
85
106
80
85
106
B
3EFWA_AK8
(AURKA)
Other
3efw
I
100
59
105
100
59
105
B
2ITWA_STU
(EGFR)
Other
staurosporine
I
80
85
106
80
85
106
B
3BKBA_STU
(FES)
Other
staurosporine
I
131
107
138
131
107
138
B
3CBLA_STU
(FES)
Other
staurosporine
I
131
107
138
131
107
138
B
3CD3A_STU
(FES)
Other
staurosporine
I
131
107
138
131
107
138
B
2X9FA_X9F
(EPHB4)
Other
X9F
I
46
19
86
46
19
86
D
1
1R0PA_KSA
(MET)
Other
k-252a
I
28
79
64
D
1R0PA_KSA
(MET)
Other
k-252a
I
28
79
64
28
79
64