Allelic Variants
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There are no related allelic variants
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| Number of involved diseases in the family |
50 |
| Number of PLK1 related diseases |
0 |
All kinase in this family
PLK1
Allelic
Variants |
Disease Description |
Involved kinases
(This family) |
Inhibitor of
Involved Kinases |
Search
Disease |
| Prostate cancer | CDK2, CHEK2, FGFR1, FGFR2,
GSK3B, PDPK1 | 6 | Link | | n/a | Measles | CDK2, EIF2AK2, GSK3B, IRAK4 | 3 | Link | | n/a | Epstein-Barr virus infection | CDK2, EIF2AK2, GSK3B, MAPK12 | 3 | Link | | n/a | Influenza A | EIF2AK2, GSK3B, IRAK4,
MAPK12 | 2 | Link | | n/a | Hepatitis C | EIF2AK2, GSK3B, MAPK12 | 2 | Link | | Jackson-Weiss syndrome | FGFR1, FGFR2 | 3 | Link | | n/a | Pertussis | IRAK4, MAPK12 | 1 | Link | | n/a | Leishmaniasis | IRAK4, MAPK12 | 1 | Link | | n/a | Chagas disease | IRAK4, MAPK12 | 1 | Link | | n/a | Toxoplasmosis | IRAK4, MAPK12 | 1 | Link | | n/a | Herpes simplex infection | CDK2, EIF2AK2 | 2 | Link | | Pfeiffer syndrome | FGFR1, FGFR2 | 3 | Link | | Lung cancer | CDK2, PTK2 | 2 | Link | | n/a | Tuberculosis | IRAK4, MAPK12 | 1 | Link | | Gastric cancer | FGFR2 | 2 | Link | | Melanoma | FGFR1 | 1 | Link | | Trigonocephaly | FGFR1 | 1 | Link | | Osteoglophonic dysplasia | FGFR1 | 1 | Link | | Kallmann syndrome | FGFR1 | 1 | Link | | Breast cancer | CHEK2 | 1 | Link | | Hypogonadotropic hypogonadism | FGFR1 | 1 | Link | | Mental retardation | CASK | 2 | Link | | n/a | FG syndrome | CASK | 2 | Link | | Li-Fraumeni syndrome | CHEK2 | 1 | Link | | n/a | Antley-Bixler syndrome without genital anomalies or disordered steroidogenesis | FGFR2 | 2 | Link | | n/a | Bladder cancer | DAPK1 | 2 | Link | | Osteosarcoma | CHEK2 | 1 | Link | | Beare-Stevenson cutis gyrata syndrome | FGFR2 | 2 | Link | | Apert syndrome | FGFR2 | 2 | Link | | n/a | Invasive pneumococcal disease | IRAK4 | 1 | Link | | Hyperinsulinemic hypoglycemia | INSR | 3 | Link | | Diabetes mellitus | INSR | 3 | Link | | IRAK4 deficiency | IRAK4 | 1 | Link | | n/a | Amyotrophic lateral sclerosis | MAPK12 | 1 | Link | | n/a | Amoebiasis | PTK2 | 2 | Link | | n/a | Salmonella infection | MAPK12 | 1 | Link | | n/a | Shigellosis | MAPK12 | 1 | Link | | n/a | Epithelial cell signaling in Helicobacter pylori infection | MAPK12 | 1 | Link | | Rabson-Mendenhall syndrome | INSR | 3 | Link | | n/a | Leprechaunism | INSR | 3 | Link | | Craniosynostosis | FGFR2 | 2 | Link | | Craniofacial-skeletal-dermatologic dysplasia | FGFR2 | 2 | Link | | Bent bone dysplasia syndrome | FGFR2 | 2 | Link | | Colon cancer | AURKA | 3 | Link | | Crouzon syndrome | FGFR2 | 2 | Link | | LADD syndrome | FGFR2 | 2 | Link | | n/a | Basal cell carcinoma | GSK3B | 2 | Link | | n/a | Scaphocephaly and Axenfeld-Rieger anomaly | FGFR2 | 2 | Link | | Scaphocephaly | FGFR2 | 2 | Link | | n/a | Saethre-Chotzen syndrome | FGFR2 | 2 | Link |
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